Double-blind evaluation of ritodrine sustained release for oral maintenance of tocolysis after active preterm labour

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Double-blind evaluation of ritodrine sustained release for oral maintenance of tocolysis after active preterm labour.

OBJECTIVE To evaluate the effect of ritodrine sustained release capsules for maintaining uterine quiescence after successful treatment of active preterm labour. DESIGN Multicentre placebo-controlled trial. SETTING Five teaching hospitals in the Netherlands. PARTICIPANTS Women (n = 95) at less than 35 weeks of gestation in whom active preterm labour had been stopped with intravenous ritodr...

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Ritodrine in oral maintenance of tocolysis after active preterm labor: randomized controlled trial.

AIM To assess the efficacy of oral ritodrine in the form of sustained-release capsules for maintenance of uterine quiescence after successful treatment of threatened preterm labor. METHODS We randomized 120 women with singleton pregnancy who were successfully treated for threatened preterm labor before 34 completed weeks to receive either maintenance tocolysis with two 40 mg ritodrine sustain...

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Tocolysis with Ritodrine: a Comparative Study in Preterm Labour

Objective: Preterm delivery is an important cause of perinatal morbidity and mortality. This study was conducted with an objective to assess the effect of ritodrine on perinatal mortality as compared to isoxsuprine and the effect of ritodrine on maternal morbidity and neonatal morbidity in comparison to isoxsuprine with the extent to which delivery was delayed. Design: A randomized study with 2...

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Prevention of Preterm Labour: 2011 Update on Tocolysis

The aim of this paper is to review available data about drugs for preventing preterm labour. Tocolytic therapy includes β adrenergic receptor agonists, NO donors, magnesium sulphate, prostaglandin-synthase inhibitors, oxytocin receptor antagonists, calcium-channel blockers, progesterone, 17-α-hydroxyprogesterone caproate, and antibiotics. Their specific effects on myometrial contractility, thei...

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Ritodrine in the treatment of preterm labour: a meta-analysis.

BACKGROUND & OBJECTIVES Results on the effect of ritodrine in the treatment of preterm labour are different all over the world. Therefore, a concrete conclusion cannot be drawn from a single randomized control trial (RCT). In this study, we selected a large number of RCTs worldwide on the treatment of preterm labour comparing ritodrine and placebo or magnesium sulfate and by applying meta-analy...

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ژورنال

عنوان ژورنال: BJOG: An International Journal of Obstetrics and Gynaecology

سال: 1996

ISSN: 1470-0328,1471-0528

DOI: 10.1111/j.1471-0528.1996.tb09841.x